As we approach the business end of the season, one of the most intriguing games of the weekend sees Alan Shearer's Newcastle United travel to Stoke City.
For the neutrals, it will be an absorbing affair with much at stake, but for fans of Newcastle and Stoke it is bound to be angst-ridden in some respects.
At the other end of the table, Liverpool kick things off against Blackburn Rovers, aiming to swiftly erase the memories of Wednesday night by going back to the top of The Premier League.
Manchester United are at Sunderland with plenty of question marks being asked of their current form.
Five other matches take place at 3pm on Saturday, including Chelsea versus Bolton Wanderers and two crunch clashes towards the bottom between Middlesbrough and Hull City plus Portsmouth and West Brom.
Then comes the Britannia Stadium blockbuster with Shearer knowing Newcastle need a positive result from one of the toughest places to go in the division.
On Sunday, we have more live action with Aston Villa entertaining Everton in a game that will go a long way to deciding who is likely to finish fifth. David Moyes's Toffees are in good form but Villa showed signs of finally getting back to their best at Old Trafford last weekend.
Liverpool v Blackburn
Chelsea v Bolton
Middlesbrough v Hull City
Portsmouth v West Brom
Sunderland v Man United -
Tottenham v West Ham
Wigan v Arsenal Stoke City v Newcastle
Aston Villa v Everton
Man City v Fulham