The 41-year-old actress, who has three children, Violet, seven, Seraphina, four, and son Samuel, 17 months, with her Oscar-winning husband of eight years, admitted she wouldn't be surprised if he decides to run for an election in the future.
The 'Dallas Buyers Club' star said: "Right now [Ben] feels like he can do more good for people politically from outside the system.
"Would I be surprised if one day he did go into politics? No. But not now."
She added to Allure magazine: "I'm along for the ride."
Ben, 40, who is an outspoken human rights activist for the Congo and founded the Eastern Congo Initiative in 2010, previously hinted he wanted to pursue a career in the US Senate.
When asked previously if he would ever run for election, the 'Argo' star said: "One never knows. I'm not one to get into conjecture. I do have a great fondness and admiration for the political process in this country. It's a big deal for me to come down here and be on your show that I've watched so much, but I'm not going to get into speculation about my political future."