'Harry Potter and the Deathly Hallows: Part 2' took home four accolades, including Best Movie, but none of the cast of the last installment of the wizard movie franchise made the trip to the US meaning their achievements were not announced in the two-hour televised ceremony, which was hosted by 'The Big Bang Theory' actress Kaley Cuoco.
Emma Stone was stunned to receive a standing ovation from the crowd as she was announced as the Best Movie Actress.
The 'Crazy Stupid Love' star - who was also awarded Best Comedic Movie Actress - told the audience: "I moved to LA eight years ago this week with my mum, who's right there. It is so insane to be standing up here right now."
Other winners at the spectacle included Johnny Depp, who won Best Movie Actor, Lea Michele, who took home the statuette for Best TV Comedy Actress and Bruno Mars, who was named Favourite Male Artist.
Robert Pattinson was on hand to accept the prize for Favourite Drama Movie for his film 'Water For Elephants' and showed off a new cropped hairstyle.
Guests included Kelly Osbourne and her mother Sharon, Miley Cyrus and her boyfriend Liam Hemsworth and Adam Sandler.
People's Choice Awards 2012:
Movie: 'Harry Potter and the Deathly Hallows: Part 2'
Movie Actor: Johnny Depp
Movie Actress: Emma Stone
Movie Icon: Morgan Freeman
Action Movie: 'Harry Potter and the Deathly Hallows: Part 2'
Action Star: Hugh Jackman
Drama Movie: Water for Elephants
Comedy Movie: Bridesmaids
Comedic Movie Actor: Adam Sandler
Comedic Movie Actress: Emma Stone
Ensemble Movie Cast: 'Harry Potter and the Deathly Hallows: Part 2'
Movie Star Under 25: Chloo Moretz
Animated Movie Voice: Johnny Depp as Rango, Rango
Movie Superhero: Ryan Reynolds, Green Lantern
Favourite Book Adaptation: 'Harry Potter and the Deathly Hallows: Part 2'
Favourite Male Artist: Bruno Mars
Female Artist: Katy Perry
Song of the Year: 'E.T.', Katy Perry, featuring Kanye West
Album of the Year: Born This Way, Lady Gaga
Pop Artist: Demi Lovato
Hip-Hop Artist: Eminem
R&B Artist: Rihanna
Band: Maroon Five
Country Artist: Taylor Swift
Music Video: 'Last Friday Night (TGIF)', Katy Perry
Tour Headliner: Katy Perry