The former 'Charmed' actress - who was previously engaged to rock star Marilyn Manson - is to tie the knot to her boyfriend, artist Davey Detail, her representative confirms to E! News.
Davey is part of the artist collective, Cyrcle, and has been linked to the 'Grindhouse' star for just over one year.
Rose recently sparked speculation that she is engaged after being spotted with a large diamond ring on her wedding finger.
The 39-year-old beauty was previously engaged to 'Beautiful People' rocker Marilyn Manson, but she ended their three-and-a-half year relationship in 2001 citing a "lifestyle difference".
She said at the time: "There is great love, but our lifestyle difference is, unfortunately, even greater."
Rose was also set to wed her 'Grindhouse' director Robert Rodriguez after they began a relationship while filming the movie in 2007. The pair were expected to marry in 2009, but announced their split in October of that year.
At the time, the actress was accused of embarking on an affair with Robert, 45, which allegedly resulted in the end of his 16-year marriage to producer Elizabeth Avellan.