Star of the upcoming film “Wolf of Wall Street” Matthew McConaughey is taking on a new and challenging role in “Dallas Buyers Club.” McConaughey lost a dramatic amount of weight to play the HIV patient.

“Dallas Buyers Club” is about real life Texas cowboy Ron Woodroof’s battle with HIV. Woodroof is diagnosed as HIV positive in 1985 and given 30 days to live. Shunned by his former friends,  Woodroof searches for alternative treatments, both legal and illegal from around the world in a “buyers club” full of outcasts like himself.

The film also stars Jennifer Garner as his doctor and Jared Leto as a fellow HIV patient. “Dallas Buyers Club” is directed by Jean-Marc Vallee, who directed “The Young Victoria” and is written by Craig Borton and Melisa Wallack of “Kill Bill.”

“Dallas Buyers Club” comes to theaters November 1, 2013.

Watch the trailer for “Dallas Buyers Club” here:

Matthew McConaughey as Ron Woodroof in “Dallas Buyers Club”Wetpaint