Louisa Harland, Caroline Menton, Danielle Galligan, Máiréad Tyers, and Stefanie Preissner as the Walsh sisters in RTÉ's upcoming series.James Pierce/RTÉ

RTÉ has revealed a first look at the cast of the eagerly anticipated comedy drama series "The Walsh Sisters," based on the novels of best-selling Irish author Marian Keyes.

The six-part series will air on RTÉ One and RTÉ Player this autumn. 

Part based on the blockbuster novels 'Rachel’s Holiday' and "Anybody Out There," the show follows the lives of sisters Anna, Rachel, Maggie, Claire and Helen as they navigate the peaks and troughs of their late 20s and 30s.

Louisa Harland ("Derry Girls," "Renegade Nell") stars as the troubled Anna Walsh, while  rising talent Caroline Menton ("Oddity") takes on the role of one of Marian’s most loved characters, sister Rachel. Danielle Galligan ("House of Guinness", "Shadow and Bone") plays eldest sister Claire and BAFTA-nominated Máiréad Tyers ("Extraordinary," "My Lady Jane," "Belfast") plays Helen. The final Walsh sister, Maggie, is played by stage, screen and screenwriting talent Stefanie Preissner ("Solpadeine is My Boyfriend," "Can’t Cope, Won’t Cope").  

"It's impossible to overstate how thrilled I am with this production," said Marian Keyes. "Stefanie Preissner's scripts alchemised the vibe of my novels into a new and compelling thing. Individually and collectively the five young women playing the sisters astonished me.

"Their warm, bickery engagement feels just like a family. The rest of the cast is equally tremendous, and Mammy and Daddy Walsh are beautiful together. These amazing people have captured the spirit of my books, and they're transformed into something new and exciting.

"Visiting the set was always a thrill, the director and crew had a definite vision, and their commitment and hard work was clear. There's a lot that's very funny and warm but some of the scenes are dark and deeply moving. This probably sounds like a strange thing to say but even if I wasn't involved in this, I'd be dying to see it. I'm so grateful to all the individuals who worked so hard to make this beautiful series and I'm very excited for the world to see the finished product.” 

The series also stars Aidan Quinn ("Legends of the Fall") as Jack 'Daddy’ Walsh, alongside Carrie Crowley ("An Cailín Ciúin") as Mammy,  Additional cast includes Jay Duffy, Samuel Anderson, and Debi Mazar. 

"The Walsh Sisters" is adapted by Stefanie Preissner, with Kefi Chadwick as additional writer, and directed by Ian Fitzgibbon. Patrick O’Donoghue is the producer.

The series is produced by Cuba Pictures and Metropolitan Pictures for RTÉ in association with the BBC, Screen Ireland and Cineflix Rights.