Ryan Fitzpatrick had his fifth fourth quarter comeback victory as he led the Buffalo Bills to a 38-35 win against the Oakland Raiders.
Kevin Kolb's 73 yard touchdown pass to Larry Fitzgerald allowed the receiver to tie Roy Green for a Cardinals' franchise record in touchdown receptions.
Adrian Peterson has 53 career rushing touchdowns for the Minnesota Vikings, that is already the most in franchise history.
Including last season's playoff game, the Kansas City Chiefs are now 119-17 in their last three games. The loss of Jamaal Charles for the season with a suspected torn ACL will only worsen the mood in Arrowhead Stadium.
Donovan McNabb surpassed his 39 yards passing from last week in the first quarter of their clash with the Tampa Bay Buccaneers. However Josh Freeman once again owned the fourth quarter. Of Freeman's 14 career victories, eight have now come when the Buccaneers went ahead in the fourth quarter of overtime. He is definitely the comeback kid of the NFL.
As a Tarvaris Jackson-led Seattle Seahawks were shut out by the Pittsburgh Steelers, Matt Hasselbeck threw for 358 yards in a Tennessee Titans' victory over the Baltimore Ravens. The Ravens' offense was grounded after last week's demolition of the Steelers, as Joe Flacco was sacked three times, threw two interceptions and had one fumble.
The New England Patriots became the first team in the past 10 seasons with a 99-yard touchdown drive in back to back games. They are also the fourth team in the past 10 years with two in a season, after only the second week of the year!
Mike Wallace became only the second Pittsburgh Steelers' player since 1970 to open the season with back to back 100 yard receiving games. Plaxico Burress being the other in 2003.
Devery Henderson's 79 yard touchdown was his fourth career receiving touchdown of 70+ yards, that is twice as many as any other player in Saints' history. Drew Brees also notched his first ever victory against the Chicago Bears after losing his previous four games.
The Seattle Seahawks are now 6-20 on the road since 2008.
Tim Tebow finally got on the field for the Denver Broncos. However Kyle Orton remained the quarterback, the injury to Brandon Lloyd entering the game meant the Broncos needed an emergency receiver. Tebow stepped up and played in the slot for his team.
Antonio Gates was targeted 13 times in Week 1, the most of any receiver/tight end. He wasn't targeted in the Chargers' game with the Patriots until the third quarter. His first target was an interception to Patriots' safety Sergio Brown in the endzone.
Week 2 of the NFL season had no inter-divisional matchups. That is the first time that that has happened since 1970.
Fittingly, Matt Schaub's 80th touchdown for the Houston Texans was thrown to Andre Johnson.
Through two NFL games, rookie quarterback Cam Newton is on pace for 6,832 yards this season. His 432 yards through the air against the Green Bay Packers, was the most for any rookie ever. Newton shattered the record for passing yards in the first two games of a career with 854 yards, surpassing the previous record of 638 by Todd Marinovich.
Furthermore only six quarterbacks all time have thrown for over 400 yards in back to back games, Newton has done it in his first two games.
Blaine Gabbert made his debut for the Jacksonville Jaguars after Luke McCown had a 1.75 passer rating.
Charles Woodson, of the Green Bay Packers, had two interceptions of Cam Newton in Week 2. That is the fourth Heisman quarterback he has picked a pass off of—Newton, Leinart, Palmer and Testaverde.
Santana Moss' touchdown against the Cardinals made it the 141st consecutive NFL weekend that a Miami player scored a touchdown. Miami led all colleges with 42 players on kickoff weekend rosters.
Drew Brees got his 50th victory as a New Orleans Saints quarterback.
After Cam Newton became the sixth ever player to have back to back 400 yard games, Tom Brady joined him the same night against the San Diego Chargers. Brady is the first player in NFL history to follow a 500 yard game with a 400 yard game.
The Buffalo Bills have 79 points through Week 2, second most in franchise history. The only time they had more, 87 in 1991, they made it to the Super Bowl.
A 19 yard completion to Deion Branch against the Chargers, moved Tom Brady to 17th all time in yards ahead of Jim Kelly who had 35,467 for his career.
The Patriots have won 10 consecutive NFL regular season games—their last loss coming against the Cleveland Browns—scoring at least 30 points in each of those victories.
Bill Belichick is now the second NFL head coach in history with three different 10 game win streaks. Don Shula is the other with four.
In 2000 Kurt Warner set a record for the most passing yards in the first two weeks of the season with 827, that record was broken by twice today, first by Cam Newton with 854 and then Tom Brady with 940.Tweeting about everything and anything.