These Patricks are famous, but they're not all saints!

Pat O'Brien

O'Brien was born William Joseph Patrick O'Brien to an Irish-American Catholic family in Milwaukee, Wisconsin. He served as an altar boy and later attended Marquette Academy with fellow actor Spencer Tracy, and later attended Marquette University. O'Brien appeared with James Cagney in nine feature films, including "Angels with Dirty Faces" and Cagney's last film, "Ragtime" in 1981. He began appearing in movies (many times playing Irish cops or priests) in the 1930s, starting with the role of ace reporter Hildy Johnson in the original version of "The Front Page" in 1931. He appeared in the highly successful 1946 suspense film, "Crack-Up" and played the lead in "The Personality Kid." O'Brien may be best remembered for his role as a police detective opposite George Raft in "Some Like It Hot" and the title role of a football coach in "Knute Rockne, All American," in which he gave the speech to "win just one for the Gipper," referring to recently deceased football player, George Gipp, portrayed in the film by a young Ronald Reagan. He died October 15, 1983.

Patrick Dempsey

Patrick Galen Dempsey is an American actor and race car driver, known for his role as neurosurgeon Dr. Derek Shepherd ("McDreamy") on the medical drama "Grey's Anatomy." He has also recently appeared in several films, including "Sweet Home Alabama," "The Emperor's Club," "Freedom Writers," "Enchanted," "Made of Honor," and "Valentine's Day." Dempsey was diagnosed with dyslexia at age twelve. He told Barbara Walters on her 2008 Oscar special that he thinks dyslexia "made him what he is today. It's given me a perspective of -- you have to keep working," Dempsey told Walters. "I have never given up."

Neil Patrick Harris

Neil Patrick Harris was born June 15, 1973. Prominent roles in his acting career include the title role in "Doogie Howser, M.D.", the womanizing Barney Stinson in "How I Met Your Mother," a fictionalized version of himself in the "Harold & Kumar" series, and the title role in Joss Whedon's Emmy Award-winning musical web series "Dr. Horrible's Sing-Along Blog." He also hosted the 63rd Tony Awards in 2009 and the 61st Primetime Emmy Awards the same year. On March 7, 2010, he made a surprise appearance at the 82nd Academy Awards, delivering the opening musical number. In 2006, he revealed he was gay.

Pat Boone

Charles Eugene Boone was born June 1, 1934 and has always been known professionally as Pat Boone. He is a singer, actor and writer who was a successful pop singer in the United States during the 1950s and early 1960s. He sold over 45 million albums, had 38 Top 40 hits and starred in more than 12 Hollywood movies. Boone's talent as a singer and actor combined with his old-fashioned values contributed to his popularity in the pre-rock and roll era. He continues to entertain and perform. Boone is also a motivational speaker, a television personality, a conservative political commentator and a Christian activist, writer and preacher.

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