James Gandolfini and Eve Hewson in a scene from Enough Said.Fox Searchlight

Bono’s second eldest daughter Eve Hewson has a co-starring role in one of the year’s best reviewed movies, Enough Said, which opened last week and stars the late James Gandolfini and Julia Louis-Dreyfus.

The plaudits for the romantic comedy are pretty much universal – The New York Times called it “one of the best written film comedies in recent memory” that will “make you laugh and leave you in tears.”  Eve plays Gandolfini’s bratty daughter who is soon to depart LA for college, and there’s no doubt that the role will elevate her status on the casting radar screen.

The 22-year-old Dublin native and recent NYU grad also has another film in the can, Blood Ties, which stars Clive Owen and Marion Cotillard. Set in Brooklyn in the 1970s, the crime thriller premiered in Cannes earlier this year but doesn’t have a U.S. release date yet.

Eve has also been cast in the upcoming Steven Soderberg 10-part series for Cinemax, The Knick. The drama is set at a New York hospital in 1900, and tells the story of doctors and nurses fighting to save lives in an era when necessities like antibiotics didn’t exist.

So it appears that Eve made a wise choice in choosing an acting career, even though her dad and mom Ali were against it at first.

“Both my parents were against it,” she told the Irish Independent last year. “It’s because they know that world and it’s really hard.  The rejection is awful, the competition is terrifying and you’re constantly up and down.  They were like, ‘No, no, no, please, no!’ I had to really fight for it.”

Bono, meanwhile, will be in New York this week speaking at the annual Clinton Global Initiative gathering alongside the likes of President Obama.  He’s also due to appear at the big Global Poverty Project concert at Central Park on September 28 to present an award to Liberian President Ellen Johnson Sirleaf for her work on women’s equality.