An Irish cosmetic surgeon had admitted he administered the drug propofol on two occasions to Michael Jackson while the star lived in Ireland, but stated that he used an anesthesiologist on both occasions.
He stated it was almost impossible for Jackson to have administered the drug to himself as the defense claims.
Dr. Conrad Murray faces four years in prison over his use of the drug on Jackson the night he died and is currently on trial in Los Angeles.
Dr. Philip Treacy treated the star for the skin condition vitigo while he was recording in Ireland, he told CNN’s Dr. Drew Pinsky.
"Michael had derma fillers in his face but the area around his nose -- he was very hypersensitive because of previous surgery he had," said Dr Treacy.
"As a consequence he wanted sedation prior to getting some fillers in his face."
He said there was no way Michael could have self administered the drug.
"My most serious concern about this case is the fact that the defence said that Michael Jackson could have killed himself by giving himself a syringe of propofol and a syringe was found under the bed," Dr Treacy said.
"If you get an injection of it, there is no antidote, but it only lasts four minutes and it wears off.
"It's almost physically impossible that Michael Jackson could have killed himself," hehe added.
Dr Treacy, who has a clinic in Dublin’s exclusive Ailesbury Road, said that the doctor must have administered the dose.
"The only person that could have done it was the doctor who was there because you would have had to manually run a maintenance dose in order to keep him asleep."