Irish research makes major breakthrough in battle against Crohn’s disease
Crucial role discovered for protein Pellino3 by university researchers
Irish university researchers have claimed a major breakthrough in the battle against Crohn’s and other colon diseases.
The Irish Independent newspaper reports on the breakthrough at Maynooth University in County Kildare.
Professor Paul Moynagh led the research team at Maynooth who have discovered what they describe as a crucial role for protein in controlling unwanted inflammation in the intestine.
The professional said the identification of the protein Pellino3 may protect against the development of the incurable Crohn’s disease.
He told the paper: “My hope is that we can build on these findings and use Pellino3 as a new diagnostic for Crohn’s disease and as a target for new drug discovery.
“Our aim at NUI Maynooth is to progress this research even further and we look forward to further advancements in the area of immunology in years to come.”
Head of the Department of Biology and Director of the Institute of Immunology at the university, Professor Moynagh added that the research represents a significant breakthrough.
His team discovered that levels of Pellino3 are dramatically reduced in Crohn’s disease patients.
The Irish Independent reports that they will now use the protein as a basis for new diagnostic for Crohn’s and as a target in designing drugs to treat the illness.
The report says more than two million people across Europe suffer from some form of inflammatory colon disease.
Inflammation is the body’s response to disease-causing micro-organisms, which involves the movement of white blood cells from vessels in the infected tissue where invading micro-organisms are destroyed.
The report adds this can result in chronic inflammatory diseases with the symptoms of the diseases being dependent on the inflammation area.
When chronic inflammation occurs in the intestine, this can lead to inflammatory colon diseases. Crohn’s disease is a particularly debilitating strand of this.
The research was supported by collaborators in Trinity College Dublin and University College Cork. The finds have been accepted and published in the Nature Immunology journal.
NUI Maynooth president Professor Philip Nolan told the paper that research is about finding answers and solutions to major challenges.
He said: “Immunology is an area of strength for Ireland and developments such as this will cement our position as one of the world’s leading nations in this field.
“The findings by Prof Moynagh and his team have the potential to impact positively on many lives.”
- Gay teacher fired from Catholic school after...
- Nelson Mandela once considered a terrorist...
- Racist incidents in Ireland up by 85 percent...
- Nelson Mandela was against IRA decommissioning.
- Irish radio presenter suspended after anti-Isra
- Unionists regret US envoy Haass’ call for...
- Hollywood star Gabriel Byrne brands new Pope...
- Website attracts 80,000 Irish people ready...
- Photo shows Irish revolutionaries three years...
- Top ten negative terms used to describe Irish...
Hello everybody, my names is Cindy Davis Am from Canada i want to give thanks and honor to Dr.ATILA for the great work he did for me, he brought my loSusan Boyle reveals she has Asperger’s syndrome, high functioning autism
Many thanks for sharing your story, handsome68. It's good to be able to hear about others' experience as life isn't long enough to learn everything weGay teacher fired from Catholic school after applying for same-sex marriage license
notice how these creeps find crevices to weasle in to spread their sickness to the children.Nelson Mandela was against IRA decommissioning its arms during 2000 talks
if you don't live in ireland - you're supposed to be ashamed of claiming to be irish - take the ridicule of the occupiers propaganda that spreads far